The most common reasons for IUI are a low sperm count or decreased sperm mobility. However, IUI may be selected as a fertility treatment for any of the following conditions as well:
- Unexplained infertility
- A hostile cervical condition, including cervical mucus problems
- Ejaculation dysfunction
- Cervical scar tissue from past procedures which may hinder the sperms’ ability to enter the uterus
IUI is not recommended for the following patients:
- Women who have severe disease of the fallopian tubes.
- Women with a history of pelvic infections
- Women with moderate to severe endometriosis
Before intrauterine insemination, ovulation stimulating medications may be used, in which case careful monitoring will be necessary to determine when the eggs are mature. The IUI procedure will then be performed around the time of ovulation, typically about 24-36 hours after the surge in LH hormone that indicates ovulation will occur soon.
A semen sample will be washed by the lab to separate the semen from the seminal fluid. A catheter will then be used to insert the sperm directly into the uterus. This process maximizes the number of sperm cells that are placed in the uterus, thus increasing the possibility of conception. The IUI procedure takes only a few minutes and involves minimal discomfort. The next step is to watch for signs and symptoms of pregnancy.
The chances of becoming pregnant with multiple are increased if you take fertility medication when having IUI. There is also a small risk of infection after IUI.
The success of IUI depends on several factors. If a couple has the IUI procedure performed each month, success rates may reach as high as 20% per cycle depending on variables such as female age, the reason for infertility, and whether fertility drugs were used, among other variables. While IUI is a less invasive and less expensive option, pregnancy rates from IUI are lower than those from IVF. If you think you may be interested in IUI, talk with your doctor to discuss your options.